Seville is connected by rail with both provincial and national destinations: Cadiz, Madrid, Granada, Cordoba, Barcelona … through both conventional and trains through the AVE (high speed train).
Official website of the Santa Justa train station in Seville
The bus lines that connect the Santa Justa railway station with the rest of the city are the C-2, the C-1, line 32 and line EA.
RENFE (Spanish railway company) has an office in the center of the city in which to purchase train tickets in advance. It is located in Calle Zaragoza num. 29 (near Plaza Nueva).